Really exasperating viral protein from HIV

نویسندگان

چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Really exasperating viral protein from HIV

Two new structures shed additional light on the nuclear transport of viral transcripts.

متن کامل

HIV-1 viral protein R (Vpr) & host cellular responses.

During infection of host cells by HIV-1, active host-pathogen interactions take place. The final balance between these interactions determines the efficiency of viral infection and subsequent disease progression. HIV-infected cells respond to viral invasion with various antiviral strategies such as innate, cellular and humoral immune antiviral defense mechanisms. On the other hand, the virus ha...

متن کامل

Rotavirus NSP4 protein as a viral biotoxin selectively promotes cytotoxicity

Abstract Background and Aims: The number of new cancer cases with considerable mortality is increasing worldwide. Since the inability of current therapies in treatment of patients and prevention the progress of tumors with fewer side effects, implementation of new methods is needed. Gene therapy has widespread systemic cytotoxic effects against tumor cells. Rotavirus NSP4 has been shown to...

متن کامل

Comparative Modeling of Viral Protein R ( VpR ) from Human Immunodeficiency Virus 1 ( HIV 1 )

During Human Immunodeficiency Virus infection interactions take place between host and the pathogen. This interaction mainly determines the efficiency of viral infection and the disease progression. Human Immunodeficiency Virus infected cells responds to several antiviral immune mechanisms such as innate, cellular and humoral immune antiviral defense. This virus has also gained resistance to su...

متن کامل

Peptide inhibitors that disrupt viral-viral protein interactions in HIV-1: literature-based review

Protein-protein interactions play a key role during each stage of the viral life cycle. Thus, inhibiting viral protein-protein interactions with the peptides derived from the binding interfaces is a promising approach for potential multi-epitope based treatments. However, molecular mechanisms underlying these protein interactions are not yet fully understood. This study is focused on a comprehe...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: eLife

سال: 2015

ISSN: 2050-084X

DOI: 10.7554/elife.05169